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   <front>
      <journal-meta>
         <journal-id journal-id-type="publisher">Psychosomatic Medicine and General Practice</journal-id>
         <issn>2519-8572</issn>
		 <journal-title-group>
			<journal-title>Psychosomatic Medicine and General Practice</journal-title>
		 </journal-title-group>
         <publisher>
            <publisher-name>Private Publisher 'Chaban O. S.'</publisher-name>
         </publisher>
      </journal-meta>
      <article-meta>
         <article-id pub-id-type="publisher-id">62</article-id>
         <article-id pub-id-type="other">615.035.4</article-id>
         <article-categories>
            <subj-group>
               <subject>General Practice</subject>
			   <subject>Dietology</subject>
            </subj-group>
         </article-categories>
         <title-group>
            <article-title>Effects of dietary supplements with vitamins, minerals and fatty acids on health</article-title>
            <article-title xml:lang="uk-UA">Вплив дієтичних добавок із вітамінами, мінералами або жирними кислотами на здоров’я</article-title>
         </title-group>
         <contrib-group>
            <contrib contrib-type="author">
               <name name-style="western">
                  <surname>Bezsheiko</surname>
                  <given-names>Vitaliy</given-names>
               </name>
               <xref ref-type="aff" rid="aff1">1</xref>
               <xref ref-type="fn" rid="conf1"/>
               <xref ref-type="corresp" rid="cor1"/>
            </contrib>
            <aff id="aff1">
               <institution content-type="dept">Department of Psychosomatic Medicine and Psychotherapy, Bogomolets National Medical University</institution>
               <addr-line>
                  <named-content content-type="city">Kyiv</named-content>
               </addr-line>
               <country>Ukraine</country>
            </aff>
         </contrib-group>
         <author-notes>
            <corresp id="cor1">
               <email>vitaliybezsh@gmail.com</email>
            </corresp>
         </author-notes>
         <pub-date date-type="pub" iso-8601-date="2017-08-15" publication-format="print">
            <day>15</day>
            <month>8</month>
            <year>2017</year>
         </pub-date>
         <volume>2</volume>
         <issue>3</issue>
         <elocation-id>e020362</elocation-id>
         <permissions>
            <copyright-statement>© 2017, Bezsheiko V.</copyright-statement>
            <copyright-year>2017</copyright-year>
            <copyright-holder>Bezsheiko V.</copyright-holder>
            <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
               <license-p>This article is distributed under the terms of the <ext-link ext-link-type="uri"
                            xlink:href="http://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution License</ext-link>, which permits unrestricted use and redistribution provided that the original author and source are credited.</license-p>
            </license>
         </permissions>
         <abstract abstract-type="short">
		 <title>Abstract</title>
		 <p>According to the results of a new study the benefits of dietary supplements are questionable.</p>
		 </abstract>
         <trans-abstract abstract-type="short" xml:lang="uk">
		   <title>Анотація</title>
		   <p>Згідно із результатами нового дослідження користь від дієтичних добавок є сумнівною.</p>
         </trans-abstract>
         <kwd-group kwd-group-type="author-keywords">
            <title>Keywords</title>
            <kwd>dietary</kwd>
            <kwd>supplements</kwd>
            <kwd>minerals</kwd>
			<kwd>fatty acids</kwd>
            <kwd>health</kwd>
			<kwd>vitamins</kwd>
         </kwd-group>
      </article-meta>
   </front>
   <body>
      <sec>
         <title>Background</title>
         <p>According to various surveys dietary supplements are extremely popular among the residents of developed countries. Thus, according to the results of the US National Health and Nutrition Examination Survey about 50% of Americans take dietary supplements on a regular basis <xref ref-type="bibr" rid="bib1">1</xref>. Among dietary supplements most popular are multivitamins and minerals complexes.</p>
         <p>Sales of dietary supplements is a good business. For example, per year the US producers earn about $28 billion per year <xref ref-type="bibr" rid="bib2">2</xref>.</p>
         <p>It is believed that consumption of dietary supplements can help to improve health. Can be assumed that if vitamins and minerals are good for health, as involved in the regulation of important functions, the more they are consumed the better.</p>
         <p>The arguments of opponents of this view are based on two main points. The first is the concept of daily norms. And the average diet of modern people meets these needs perfectly, even in the case of increased needs through specific health conditions (e.g. pregnancy) or heavy exercises. Second, the absorbability of vitamins and minerals in dietary supplements usually is significantly lower than conventional products of plant / animal origin. Or there might be another option - the development of overdose with uncontrolled supplements consumption.</p>
         <p>To establish the real impact of dietary supplements on the body a team of scientists from Germany, Poland, Austria and Greece conducted an analysis of all the available evidence on this subject <xref ref-type="bibr" rid="bib3">3</xref>.</p>
      </sec>
      <sec>
         <title>Results of the new study</title>
         <p>In the analysis were included all available best-designed randomized placebo-controlled trials. Health effects were measured by such indicators as all-cause mortality, cardiovascular mortality and incidence, cancer mortality and incidence. If dietary supplements are helping to maintain health, there must be less cases of heart disease, cancer and fewer deaths in those who have used dietary supplements in compare to placebo.</p>
         <p>Scientists selected studies that used supplements containing vitamins A, B, C, D, E and various minerals (selenium, calcium, potassium, iron, zinc, iodine, copper, magnesium), fibers, probiotics, prebiotics, symbiotics, polyunsaturated fatty acids. All these substances were taken both separatly and in combination in various dosage and forms - tablets, capsules, syrups, drops, etc.</p>
         <p><bold>Overall mortality. </bold>Among all used dietary supplements there were not and significantly effects on any of measures.</p>
         <p><bold>Cardiovascular incidence and mortality. </bold>Generally only vitamin E significantly reduced the likelihood of death due to cardiovascular causes (eg, due to myocardial infarction). Those who regularly took the vitamin as a supplement, the risk of death was reduced by 12% compared to placebo. Also, among those who took folic acid, the risk of heart disease was lower by 19% compared to placebo.</p>
         <p><bold>Cancer morbidity and mortality. </bold>The additional intake of vitamin A supplements increased risk of cancer by. At the same time, consumption of calcium supplementation reduces cancer risk by 63%. There haven’t been and other significant effects noted.</p>
      </sec>
      <sec>
         <title>Conclusion</title>
         <p>So, based on these results, taking dietary supplements will certainly not help in longevity. Some positive effects may be have vitamin E, folic acid and calcium, while vitamin A supplementations are associated with some health risks. There should be noted that several studies, included in the analysis, we sponsored by the manufacturer of these supplements, and therefore, if the final results are biased, it is rather towards exaggeration of positive effects. </p>
      </sec>
   </body>
   <back>
      <fn-group>
         <title>Competing interests</title>
         <fn fn-type="conflict" id="conf1">
            <p>The author declare that no competing interests exist.</p>
         </fn>
      </fn-group>
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</article>
